sparsentan will minimize the extent or impact of modafinil by influencing hepatic enzyme CYP2C19 metabolism. Use Caution/Keep an eye on. Sparsentan (a CYP2C19 inducer) decreases publicity of CYP2C19 substrates and reduces efficacy relevant to these substrates.Hou et al (2005) studied the autonomic effects of modafinil in human beings. They found th
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